Sileo (dexmedetomidine oromucosal gel)
سيليو جل فموي مهدئ لعلاج الخوف من الأصوات الصاخبة في الكلاب
Sileo is an oromucosal gel containing 0.1 mg/mL dexmedetomidine hydrochloride. Specifically formulated for transmucosal absorption in dogs to provide anxiolysis without clinically meaningful sedation, indicated for the treatment of noise aversion (fear and anxiety associated with fireworks, thunderstorms, construction, or travel).
Dosage Form
Gel
Product Type
Pharmaceutical
Manufacturer
Package
Multi-dose oral syringe of 3 mL with 0.25 mL increment ring-stop mechanism
Dosages
| Species | Dosage | Route | Duration |
|---|---|---|---|
| Dog | 125 mcg/m2 body surface area applied to the oral mucosa between the cheek and gum | Oromucosal application | Administer at the first signs of anxiety or prior to anticipated noise event; can be re-dosed at intervals of 2 hours up to 5 times |
Withdrawal Periods
No withdrawal information available.
Indications
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Treatment of noise aversion in dogs associated with fireworks, thunderstorms, construction, gunshots, or other loud noises.
Contraindications
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Do not use in dogs with severe cardiovascular, renal, or hepatic disease.
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Do not use in dogs that are clinically depressed or lethargic.
Precautions
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Dexmedetomidine is an alpha-2 adrenoceptor agonist; monitor heart rate and mucous membrane color.
Side Effects
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Transient pale mucous membranes, sedation, bradycardia, hypothermia, or mild emesis.
Images
Documents
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Sileo (dexmedetomidine oromucosal gel) Prescribing Information
Leaflet
Active Ingredients
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Dexmedetomidine hydrochloride
100 mcg/mL (0.1 mg/mL)
Diseases
No diseases linked.
Related Products
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Companies
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Zoetis
Manufacturer
Alternatives
No alternatives available.