Depo-Medrol

ديبو-ميدرول

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Pharmaceutical Suspension

Depo-Medrol (methylprednisolone acetate) Sterile Aqueous Suspension is an anti-inflammatory corticosteroid indicated for the treatment of pain and lameness associated with osteoarthritis in horses, and for inflammatory and allergic conditions in dogs and cats.

Dosage Form

Suspension

Product Type

Pharmaceutical

Manufacturer

Zoetis

Package

Vials containing 20 mg/mL or 40 mg/mL methylprednisolone acetate in 5 mL, 10 mL, or 20 mL multi-dose vials

Dosages

Species Dosage Route Duration
Horse Usual initial dose is 200 mg (range 40 to 240 mg) intra-articular or intramuscular Intra-articular or Intramuscular (IM) Repeated at intervals depending on clinical response
Dog Average dose is 20 mg (1 to 2 mg/kg) IM; range 2 to 40 mg Intramuscular (IM) or Subcutaneous Weekly or as needed based on condition
Cat Average dose is 10 to 20 mg (range 1 to 2 mg/kg) IM Intramuscular (IM) Every 1 to 3 weeks as needed

Withdrawal Periods

No withdrawal information available.

Indications

  • Alleviation of pain and lameness associated with localized arthritic conditions and generalized osteoarthritis in horses.

  • Treatment of allergic and inflammatory dermatoses, arthritic conditions, and otitis externa in dogs and cats.

  • Management of feline asthma and eosinophilic granuloma complex in cats.

Contraindications

  • Do not use in horses with acute infectious arthritis, septic conditions, or systemic fungal infections.

  • Do not administer intravenously.

Precautions

  • Glucocorticoid administration in horses carries risk of laminitis.

  • Long-term systemic use may lead to hypothalamic-pituitary-adrenal (HPA) axis suppression, polyuria, polydipsia, and iatrogenic Cushingoid signs.

  • Ensure strict aseptic technique when performing intra-articular injections.

Side Effects

  • Polyuria, polydipsia, increased appetite, weight gain, transient muscle weakness, and risk of laminitis in equines.

Images

Documents

  • Depo-Medrol Prescribing Information

    Leaflet
    Download

Active Ingredients

Diseases

No diseases linked.

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